CJC-1295 (No DAC) + Ipamorelin Blend
CJC-1295 (No DAC) + Ipamorelin Blend

CJC-1295 (No DAC) + Ipamorelin Blend

$80
CJC-1295 + Ipamorelin: 10MG/10MG
127 pieces in stock

CJC-1295 (No DAC) & Ipamorelin Blend Description

This is a blend (20mg)  CJC-1295(No DAC) (10mg) and Ipamorelin (10mg).

Ipamorelin and CJC-1295 Description

This 20mg peptide blend contains CJC-1295 (No DAC) and Ipamorelin, each at 10mg, designed to synergistically enhance natural growth hormone (GH) secretion through complementary mechanisms.

CJC-1295 (No DAC) stimulates the body’s growth hormone-releasing hormone (GHRH) receptors, promoting a natural, rhythmic release of GH. It’s being studied for its ability to support muscle recovery, fat metabolism, and overall regenerative function.

Ipamorelin is one of the most selective GH secretagogues and acts as a ghrelin receptor agonist. Research shows it may help improve bone density, muscle regeneration, pancreatic insulin secretion, and gastrointestinal motility, all with minimal impact on cortisol or prolactin levels.

When used together, CJC-1295 and Ipamorelin have demonstrated synergistic potential, offering a more potent and physiologically balanced enhancement of endogenous GH levels. This combination is of interest in studies related to anti-aging, tissue repair, and overall metabolic optimization

Peptide Information

Specification CJC-1295 Ipamorelin
Sequence Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2 Aib-His-D-2-Nal-D-Phe-Lys-NH2
Molecular Formula C152H252N44O42 C38H49N9O5
Molecular Weight 3368.7 g/mol 711.868 g/mol
PubChem CID 56841945 9831659
CAS Number 446262-90-4 170851-70-4
Synonyms Mod GRF (1-29), CJC-1295 no DAC  NNC-26-0161；UNII-Y9M3S784Z6；IPAMORELIN ACETAT

 

CJC1295 no DAC

As a synthetic growth hormone-releasing hormone (GHRH) analog, the core mechanism of action of CJC1295 no DAC lies in its ability to significantly promote the endogenous secretion of growth hormone. By specifically binding to the corresponding receptor, this compound can not only effectively induce the pulsatile release of growth hormone, thus having a positive impact on the growth and repair process of muscle tissue, but also play a two-way regulatory role in the catabolism and anabolism of adipose tissue by regulating the energy metabolism pathway. At the same time, it can maintain and increase bone density by enhancing the activity of osteoblasts and inhibiting the function of osteoclasts.

From the perspective of basic research and clinical application, these multiple biological effects make CJC1295 no DAC an important tool in the in-depth analysis of the growth hormone secretion mechanism. Especially in the field of diagnosis and treatment of growth hormone-related diseases, for endocrine disorders such as growth hormone deficiency and childhood short stature, its characteristic of promoting hormone secretion provides an experimental basis for exploring new treatment strategies. It is worth noting that for a series of aging-related phenotypes caused by the physiological decline of growth hormone with age, including decreased skeletal muscle mass, increased body fat percentage, and decreased skin elasticity, CJC1295 no DAC shows potential anti-aging biological effects by increasing the level of growth hormone in the circulatory system. This provides a new research direction for the intervention research of aging-related diseases and the application exploration of improving the quality of life of the elderly population.

In the fields of exercise physiology and sports science, this compound has a positive effect on the muscle growth, post-exercise recovery, and improvement of athletic performance of athletes through multiple pathways such as accelerating muscle protein synthesis, promoting muscle fiber repair, and enhancing energy metabolism efficiency. Thus, it has become an important focus in the research of strategies for enhancing athletic ability in the field of sports medicine. Overall, with its unique mechanism of action and extensive biological effects, CJC1295 no DAC shows important research value and application potential in multiple fields such as basic medical research, clinical disease treatment, and sports science.

Ipamorelin

Ipamorelin is a synthetic pentapeptide compound. As an important member of the growth hormone secretagogue family, its molecular structure design endows it with the ability to precisely regulate the growth hormone secretion axis. This compound binds with high affinity to the growth hormone secretagogue receptor (GHS-R), activating the downstream signaling pathway, thus efficiently inducing the pulsatile release of growth hormone (GH) and simultaneously promoting the gene expression and protein synthesis of insulin-like growth factor-1 (IGF-1). This dual mechanism of action not only regulates the energy metabolism process (including promoting amino acid uptake, accelerating protein synthesis, and optimizing fat catabolism), but also plays a positive regulatory role in tissue repair and growth by enhancing the cell proliferation signal.

In clinical application research, Ipamorelin has shown multi-system regulatory effects: its effect on improving gastrointestinal motility is manifested as accelerating gastric emptying rate. Especially in the pathological state of postoperative ileus, it can effectively relieve intestinal motility disorders by promoting the peristaltic frequency and contraction intensity of gastrointestinal smooth muscles; in the field of pain management, this compound regulates nociceptive signal transmission through both central and peripheral pathways, showing a significant relieving effect on non-inflammatory visceral pain and somatic pain. Its mechanism of action may involve the activation of the endogenous opioid peptide system and the regulation of ion channel activity.

Compared with traditional growth hormone secretagogues, the significant advantage of Ipamorelin lies in its high selectivity for growth hormone release - while effectively stimulating GH secretion, it has no significant effect on the secretion of other pituitary-adrenal axis hormones such as adrenocorticotropic hormone (ACTH) and cortisol, thus reducing the risk of adverse reactions caused by hormonal disorders. This pharmacological property gives it the potential for precise intervention in the replacement treatment of growth hormone deficiency, and at the same time provides a new drug target for the research on the pathogenesis of gastrointestinal motility disorders and the optimization of pain diagnosis and treatment programs. Currently, based on its unique mechanism of action and safety characteristics, the translational application research of Ipamorelin in the fields of endocrine diseases, digestive system diseases, and pain medicine is continuously deepening, showing broad clinical application prospects.

Summary

Promoting Muscle Growth and Repair:

The combined use of CJC1295 No DAC and Ipamorelin can significantly increase the synthesis of muscle proteins and accelerate the repair and regeneration of muscle tissue. Its mechanism of action may involve the direct stimulation of muscle cells by growth hormone, as well as the indirect promotion of muscle growth by regulating other growth factors and metabolic pathways. In the field of sports medicine, the combined application of these two peptide substances has important value. For fitness enthusiasts, it can promote muscle recovery after exercise, enhance muscle strength and volume, and improve training effects. Studies have shown that growth hormone can activate muscle stem cells, promoting their proliferation and differentiation into mature muscle cells, thus accelerating the muscle repair process.

Optimizing Fat Metabolism:

The combined use of Ipamorelin and CJC1295 No DAC can increase the level of growth hormone, thereby promoting the decomposition and oxidation of fat. Growth hormone can increase the activity of lipolytic enzymes in fat cells, promoting the decomposition of fat into free fatty acids and glycerol to provide energy for the body. At the same time, it can also improve the utilization efficiency of fat, reduce the storage of body fat, and improve body composition. This is of great significance for fat loss and body shaping, especially for those who want to reduce their body fat percentage and improve their body lines.

Enhancing Energy Levels and Athletic Performance:

The increase in growth hormone can increase the basal metabolic rate and enhance the efficiency of energy production and utilization. An increase in the basal metabolic rate means that the body can consume more energy even at rest, which helps to maintain the body's energy balance. This enables users to obtain higher energy levels during daily activities and exercise, extend exercise endurance, and improve athletic performance.

Improving Sleep Quality:

Growth hormone plays an important role in regulating the sleep cycle and quality. The combined use of Ipamorelin and CJC1295 No DAC can improve the sleep structure and increase the deep sleep time. Deep sleep is crucial for the body's recovery and repair. It can promote the secretion of growth hormone, enhance the function of the immune system, and improve the cognitive ability of the brain.

Enhancing Immune Function:

Growth hormone supports the normal function of the immune system. It can enhance the activity and function of immune cells, improve the body's immunity, and help resist diseases. By increasing the level of growth hormone, the combined use of Ipamorelin and CJC1295 No DAC can enhance the proliferation and differentiation ability of immune cells, promote the production of antibodies, and improve the body's resistance to pathogens.

2. Application Fields

Anti-aging Medicine:

With the increase of age, the level of growth hormone in the human body gradually decreases, leading to aging phenomena such as muscle loss, fat gain, and skin relaxation. The combined use of Ipamorelin and CJC1295 No DAC can increase the level of growth hormone and has potential anti-aging effects. Researchers are exploring the application of these two peptide substances in delaying aging and improving the quality of life of the elderly. For example, they can be used to prevent and treat aging-related diseases such as senile muscle atrophy, osteoporosis, and cardiovascular diseases.

Sports Medicine:

In the sports field, the combined use of CJC1295 No DAC and Ipamorelin can promote muscle growth and repair, enhance athletic performance, and reduce the occurrence of sports injuries. Fitness enthusiasts can use these two peptide substances as an auxiliary means to improve training effects and accelerate the recovery process.

Treatment of Endocrine Diseases:

For endocrine diseases such as growth hormone deficiency and idiopathic short stature, the combined use of Ipamorelin and CJC1295 No DAC provides new ideas and methods for treatment. By regulating the secretion of growth hormone, it helps to improve the symptoms of patients and promote the normal development and growth of the body.

For Research Use Only
This compound is provided exclusively for in vitro laboratory research. It is not intended for human or animal consumption, diagnosis, treatment, or medical use. Not for dietary, cosmetic, or veterinary purposes. This product has not been evaluated by the U.S. Food and Drug Administration or any other regulatory authority.

Disclaimer
All information is for educational purposes only. Humatide makes no claims regarding efficacy or safety. Purchasers are responsible for ensuring proper handling and use in compliance with all applicable laws and regulations.

Terms of Sale
By purchasing from Humatide, you confirm that you are a qualified researcher with the knowledge and facilities to safely handle and store research chemicals. All sales are final. Humatide assumes no liability for misuse, misrepresentation, or unintended consequences arising from the use of this product.

ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE SOLELY FOR INFORMATION DISSEMINATION AND EDUCATIONAL PURPOSES.

The products provided on this website are intended exclusively for in vitro research. In vitro research (Latin: *in glass*, meaning in glassware) is conducted outside the human body. These products are not pharmaceuticals, have not been approved by the U.S. Food and Drug Administration (FDA), and must not be used to prevent, treat, or cure any medical condition, disease, or ailment. It is strictly prohibited by law to introduce these products into the human or animal body in any form.

Polypeptide Purity Control and Verification Technical System

Humatide.com provides peptides with purity exceeding 99%. Humatide achieves precise control and scientific verification of polypeptide purity by integrating advanced technologies and a full-process quality control system: In the synthesis stage, automated solid-phase peptide synthesis (SPPS) is employed to accurately assemble amino acid sequences. A gradient purification strategy ranging from medium-pressure liquid chromatography (MPLC) to preparative high-performance liquid chromatography (Prep-HPLC) is utilized, optimizing mobile phase composition and elution conditions based on the physicochemical properties of the target peptide (hydrophobicity, charge distribution, etc.) to efficiently remove impurities. For purity detection, reverse-phase high-performance liquid chromatography (RP-HPLC) serves as the core technique, separating components through the distribution difference of molecules between the stationary phase (hydrophobic packing) and the mobile phase (polar solvent). Purity is determined via retention time matching and peak area normalization. Meanwhile, electrospray ionization mass spectrometry (ESI-MS) is combined to precisely verify the molecular weight and composition through mass-to-charge ratio (m/z) analysis, eliminating structurally heterogeneous impurities. Quality management covers the entire chain from raw material acceptance, synthesis process monitoring to finished product release. A continuous quality fingerprint is constructed using multi-dimensional indicators (HPLC purity, MS molecular weight, solvent residue, etc.), and batch data traceability is achieved through a laboratory information management system (LIMS), ensuring each batch meets the prespecified purity standards. This system provides a reliable technical guarantee for preparing high-purity polypeptides through the organic integration of process optimization, multi-dimensional detection, and full-process quality control.

Concepts of High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS)

High-performance liquid chromatography (HPLC) is a separation technology widely used by Humatide for peptide purification. Driven by a high-pressure pump, the mobile phase carries samples through a chromatographic column packed with a specific stationary phase, achieving separation based on differences in the distribution coefficients of components between the two phases. It features high separation efficiency, fast analysis speed, and strong detection sensitivity, enabling precise capture of subtle differences between target peptides and impurities such as sequence analogs or deletion peptides.

Mass spectrometry (MS) is an analytical method that converts peptide molecules into gas-phase ions through ionization technology and separates/detects ions based on their mass-to-charge ratio (m/z). It can accurately determine the molecular weight of peptides and infer amino acid sequences through fragment ion information, serving as a key technology for verifying peptide structural correctness. The combination of these two techniques allows Humatide to establish a complete quality control system from both purity separation and structural confirmation perspectives. Both methods are high-precision peptide detection technologies that scientifically demonstrate the purity and composition of peptides ordered from Humatide.com.

Humatide is committed to translating cutting-edge analytical technologies into tangible quality assurance. Our peptide synthesis laboratories are equipped with high-resolution mass spectrometers and ultra-high-performance liquid chromatography systems. Through real-time detection and data comparison of samples at each production stage, we continuously optimize synthesis processes to ensure every peptide product is delivered to customers with exceptional purity.

Recommended Peptide Purity Levels

Humatide provides only the highest-purity peptides (purity ≥99%) for research and development. The minimum recommended peptide purity level for specific applications depends on the application:

• In biochemical research, peptides used for enzyme activity analysis typically require ≥85% purity.

• In drug development, peptides for preclinical trials must meet >98% high-purity standards to ensure biological activity and safety.

• For diagnostic applications (e.g., antigen peptides in immunoassays), recommended purity is 90%-95% to guarantee detection specificity and sensitivity.

Humatide is confident in the quality of all our products, implementing strict quality monitoring at every stage of peptide synthesis—from crude peptide purification to final product release. Through multi-step purification and verification processes, we ensure each batch meets or exceeds the purity requirements for specific applications. Examples of acceptable minimum purity levels are as follows:

High Purity (>95%)

• Polypeptide drug research and production

• Preparation of targeted therapeutic drugs

• Raw materials for biological diagnostic reagents (e.g., ELISA, immunoassay kits)

• Development of polypeptide vaccines (therapeutic/preventive)

• Preparation of targeting peptides for antibody-drug conjugates (ADCs)

• Polypeptide reagents for life science research (e.g., receptor agonists/antagonists)

• Research on targeting peptide modification for gene therapy vectors

• Development of polypeptide antibiotics/antimicrobial peptides

• Preparation of polypeptide hormone analogs (e.g., insulin analogs)

• Reference standards for biomarker detection

• Research on cell culture additives

• Synthetic peptides for protein structure analysis and functional studies

Moderate Purity (>85%)

• Early-stage activity screening in polypeptide drug research

• Peptide additives for industrial enzymes

• Signal peptide raw materials

• Surface modification of biomaterials (e.g., medical catheters, tissue engineering scaffolds)

• Preparation of agricultural antimicrobial peptides

• Cell adhesion research

• Raw materials for polypeptide surfactants/detergents

• Polypeptide reagents for preliminary mechanistic research in scientific studies

Lower Purity (>70%)

• Preliminary structure-activity relationship (SAR) studies

• Initial verification of protein binding

• Primary cytotoxicity screening

• High-throughput screening of polypeptide drug lead compounds


Please note

**We are not responsible for reconstitution or any issue that arise from it**


High-purity polypeptides are suitable for scenarios requiring strict purity. The ultra-high-purity peptides provided by Humatide can meet and exceed all prespecified purity standards.

Humatide Shipping & Delivery

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Refund Policy
Due to the sensitive nature of research products, all sales are final.
We cannot accept returns or issue refunds once an order has been shipped. This policy helps ensure product integrity and safety for all of our research partners.

Damaged or Defective Items

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To View the latest Certificate of Analysis (CoA) click the "View Latest 3rd Party Certificate of Analysis" button on the product page.  Please use that if you are looking to buy as that is the batch you'll receive if you place an order.  The QRCode will give you the Batch ID/Lot Number which is matched on the CoA to validate that CoA matches your specific vial.  If you happen to get a vial that is from a previous batch select the "Previous Batch 3rd Party Certificate of Analysis" if your Batch ID doesn't match the latest CoA.   

All CoA are searchable via the respective testers' website. 

ILS Labs Verification is available on their website at:  

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To validate the CoA on the ILS Labs website enter the Access Code that is located on the bottom of the CoA that is shown on our website.   

We also use MDx Biolabs, verification is available via their website at:  

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To find validate the CoA on the MDx Biolabs website enter the COA number which is located at the bottom of the CoA that is shown on our website.  

 

 

 

CJC-1295 (No DAC) + Ipamorelin Blend
CJC-1295 (No DAC) + Ipamorelin Blend
10MG/10MG
$80

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