{"product_id":"bpc157-tb500","title":"KLOW Blend","description":"\u003ch2\u003e\u003cstrong\u003eBPC-157 + TB-500 + KPV + GHK-Cu Blend Description\u003c\/strong\u003e\u003c\/h2\u003e\n\u003cp class=\"whitespace-pre-wrap break-words\"\u003e\u003cem\u003eThis is a blend (80mg) each of BPC-157 (10mg) + TB-500 (10mg) + KPV (10mg) + GHK-Cu (50mg).\u003c\/em\u003e\u003c\/p\u003e\n\u003cp class=\"whitespace-pre-wrap break-words\"\u003eKlow is a blend comprising TB4, BPC-157, KPV, and GHK-CU. TB4(TB-500) modulates actin dynamics to promote cell migration, angiogenesis, and collagen synthesis, supporting connective tissue regeneration; BPC-157 upregulates relevant factor expression, enhances angiogenesis and fibroblast activity, repairs multiple tissues, and provides cellular protection; KPV suppresses pro-inflammatory factors, reduces inflammation, and promotes mucosal repair; GHK-Cu stimulates collagen production, regulates inflammation and antioxidant activity, and supports tissue repair. The four peptides complement each other: TB500 and BPC-157 provide migration-angiogenesis-matrix templating, KPV blocks inflammatory negative feedback, while GHK-Cu stabilizes collagen cross-linking and scavenges free radicals. This forms an “anti-inflammatory-migration-regeneration-remodeling” closed loop, enabling Klow to significantly accelerate repair, reduce scarring, and restore function in soft tissue injuries, postoperative healing, skin aging, and mucosal ulcers..\u003c\/p\u003e\n\u003ch3\u003ePeptide Information\u003c\/h3\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003e\u003cstrong\u003eSpecification\u003c\/strong\u003e\u003c\/th\u003e\n\u003cth\u003e\u003cstrong\u003eBPC-157\u003c\/strong\u003e\u003c\/th\u003e\n\u003cth\u003e\u003cstrong\u003eGHK-Cu\u003c\/strong\u003e\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSequence\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan style=\"font-weight: 400;\"\u003eLys–Pro–Val\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003eGly-His-Lys\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular Formula\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eC₁₆H₃₀N₄O₄\u003c\/td\u003e\n\u003ctd\u003eC\u003csub\u003e28\u003c\/sub\u003eH\u003csub\u003e46\u003c\/sub\u003eCuN\u003csub\u003e12\u003c\/sub\u003eO\u003csub\u003e8\u003c\/sub\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular Weight\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\n\u003cspan class=\"akGp8\"\u003e\u003cspan\u003e342.43\u003c\/span\u003e\u003c\/span\u003e g\/mol\u003c\/td\u003e\n\u003ctd\u003e744.3 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003ePubChem CID\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e125672\u003c\/td\u003e\n\u003ctd\u003e9831891\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eCAS Number\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e67727-97-3\u003c\/td\u003e\n\u003ctd\u003e130120-56-8\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSynonyms\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan style=\"font-weight: 400;\"\u003eACTH(11-13), alpha-MSH(11-13)\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003eThymosin-β4 fragment 17-23, TB-500 acetate, Ac-LKKTETQ\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ctable\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003e\u003cstrong\u003eSpecification\u003c\/strong\u003e\u003c\/th\u003e\n\u003cth\u003e\u003cstrong\u003eKPV\u003c\/strong\u003e\u003c\/th\u003e\n\u003cth\u003e\u003cstrong\u003eGHK-Cu\u003c\/strong\u003e\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSequence\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cspan style=\"color: rgb(28, 27, 27); font-family: Prompt, sans-serif; font-size: 9.6px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: 0.4px; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: rgb(241, 241, 241); text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial; display: inline !important; float: none;\"\u003eLys–Pro–Val\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd\u003eAc-Leu-Lys-Lys-Thr-Glu-Thr-Gln (Ac-LKKTETQ)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular Formula\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eC₆₂H₉₈N₁₆O₂₂\u003c\/td\u003e\n\u003ctd\u003eC₃₈H₆₈N₁₂O₁₄\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eMolecular Weight\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e1419.5 g\/mol\u003c\/td\u003e\n\u003ctd\u003e889.0 g\/mol\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003ePubChem CID\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e9941957\u003c\/td\u003e\n\u003ctd\u003e62707662\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eCAS Number\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e137525-51-0\u003c\/td\u003e\n\u003ctd\u003e885340-08-9\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSynonyms\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003ePL-14736, Body-Protection Compound-157, Bepecin\u003c\/td\u003e\n\u003ctd\u003eBisprezatide copper；DL1TR6W6VM\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cdiv id=\"prod_describe_new_0\" class=\"prod_describe_new3 prod_new_active3\"\u003e\n\u003cdiv class=\"prod_describe_new_content\"\u003e\n\u003cdiv class=\"prodDetail-editor-container sliderTable\"\u003e\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv id=\"prod_describe_new_1\" class=\"prod_describe_new3\"\u003e\n\u003cdiv class=\"prod_describe_new_content\"\u003e\n\u003cdiv class=\"prodDetail-editor-container sliderTable\"\u003e\n\u003cdiv class=\"prod_describe_new3 prod_new_active3\" id=\"prod_describe_new_0\"\u003e\n\u003cdiv class=\"prod_describe_new_content\"\u003e\n\u003cdiv class=\"prodDetail-editor-container sliderTable\"\u003e\n\u003cp style=\"text-align: left;\"\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 24px;\"\u003eWhat is TB4(TB-500)?\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eTB4 is a synthetic peptide composed of 43 amino acids. Its sequence exhibits high homology with the active fragment of thymosin β4 (Tβ4), a multifunctional peptide naturally present in the human body that extensively participates in physiological processes such as cellular repair and inflammation regulation. The core mechanism of TB4 involves binding to actin on the cell surface to regulate cytoskeletal reorganization, thereby significantly promoting cell migration and tissue regeneration. In muscle, tendon, or ligament injury models, TB4 accelerates the aggregation of fibroblasts at the injury site, promotes the orderly arrangement of collagen fibers, shortens the healing cycle, and reduces the likelihood of scar tissue formation. TB4 induces angiogenesis by stimulating cytokine expression (e.g., vascular endothelial growth factor, VEGF), improving blood perfusion in injured areas to deliver ample oxygen and nutrients for tissue repair. It inhibits pro-inflammatory factor release (e.g., TNF-α, IL-6) and modulates macrophage polarization, thereby reducing post-injury inflammatory responses at the immunoregulatory level and preventing tissue damage from excessive inflammation.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"prod_describe_new3\" id=\"prod_describe_new_1\"\u003e\n\u003cdiv class=\"prod_describe_new_content\"\u003e\n\u003cdiv class=\"prodDetail-editor-container sliderTable\"\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cspan style=\"font-size: 24px;\"\u003eWhat is BPC-157?\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eBPC-157 is a synthetic peptide composed of 15 amino acids. Its sequence originates from the Body Protection Compound (BPC) fragment within human gastric mucosal proteins, serving as an artificial analog of endogenous gastrointestinal protective peptides. The core biological characteristic of this peptide lies in its potent tissue repair regulatory capacity. It promotes proliferation and migration of repair-related cells like fibroblasts and endothelial cells by activating tyrosine kinase receptors (e.g., c-Met), while accelerating synthesis and remodeling of extracellular matrix components (e.g., collagen, fibronectin). This effect has been validated in models of gastrointestinal ulcers, tendon ruptures, and bone defects. In gastric mucosal injury models, BPC 157 significantly shortens ulcer healing time and improves mucosal regeneration quality.\u003c\/p\u003e\n\u003cp\u003eBPC 157 exerts a key role by modulating the inflammatory microenvironment. It suppresses neutrophil infiltration and the overexpression of pro-inflammatory factors (such as IL-1β and NF-κB), while simultaneously upregulating the secretion of anti-inflammatory factors (such as IL-10). This mitigates the acute inflammatory response following injury and prevents secondary tissue damage caused by uncontrolled inflammation. Its vasoprotective effects are particularly pronounced. By stimulating the release of vascular endothelial growth factor (VEGF) and angiopoietin, it promotes the formation of a new vascular network in damaged areas, improves local blood perfusion, and provides adequate nutrient and oxygen supply for tissue repair.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"prod_describe_new3\" id=\"prod_describe_new_2\"\u003e\n\u003cdiv class=\"prod_describe_new_content\"\u003e\n\u003cdiv class=\"prodDetail-editor-container sliderTable\"\u003e\n\u003cp\u003e\u003cspan style=\"font-size: 24px;\"\u003e\u003cstrong\u003eWhat is KPV?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eKPV, a tripeptide composed of lysine-proline-valine, originates from the C-terminal region of α-melanocyte-stimulating hormone (α-MSH) and is a naturally occurring fragment with significant biological activity.\u003c\/p\u003e\n\u003cp\u003eIn inflammation regulation, KPV exhibits potent anti-inflammatory activity. It effectively suppresses the nuclear factor-κB (NF-κB) signaling pathway, reducing the transcription and release of pro-inflammatory cytokines (such as IL-1β, TNF-α, etc.), thereby curbing inflammatory cascades at their source. In animal models of colitis, oral administration of KPV significantly reduces intestinal inflammation levels and alleviates mucosal damage. This effect stems from its precise regulation of inflammatory signaling in intestinal immune cells and epithelial cells. KPV further mitigates local inflammatory responses by stabilizing mast cells and reducing the release of inflammatory mediators like histamine, thereby maintaining tissue homeostasis.\u003c\/p\u003e\n\u003cp\u003eAt the immunoregulatory level, KPV demonstrates bidirectional modulation capabilities. It enhances T-cell differentiation and function, promotes the secretion of immunoregulatory factors like IL-2 and IFN-γ, and boosts cellular immune responses. In autoimmune disease models, KPV regulates Th1\/Th2 cell balance, reduces excessive autoimmune reactions, and prevents immune damage.\u003c\/p\u003e\n\u003cp\u003eKPV also holds potential value in cellular proliferation and tissue repair. By activating relevant intracellular signaling pathways, it promotes fibroblast proliferation and migration, accelerates the synthesis of extracellular matrix components like collagen, and facilitates wound healing in tissues such as skin and muscle. In skin repair experiments, KPV-treated wounds exhibited significantly accelerated healing rates and reduced scar formation, demonstrating its positive impact on tissue repair quality. KPV may also stimulate the expression of angiogenesis-related factors like vascular endothelial growth factor (VEGF), promoting neovascularization and improving blood supply to injured sites, thereby providing essential conditions for tissue regeneration.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"prod_describe_new3\" id=\"prod_describe_new_3\"\u003e\n\u003cdiv class=\"prod_describe_new_content\"\u003e\n\u003cdiv class=\"prodDetail-editor-container sliderTable\"\u003e\n\u003cp\u003e\u003cspan style=\"text-wrap-mode: wrap; font-size: 24px;\"\u003e\u003cstrong\u003eWhat is GHK-Cu?\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eGHK-Cu is a complex formed by glycyl-L-histidyl-L-lysine tripeptide and copper ions. Leveraging the synergistic action of copper ions and the tripeptide, it performs multiple critical functions in physiological activities. In skin repair and regeneration, it acts as a signaling peptide to induce fibroblasts to synthesize collagen, elastin, and glycosaminoglycans, enhancing skin firmness and elasticity while improving skin issues caused by aging or photoaging. During wound healing, it stimulates stratum corneum cell growth to accelerate closure while regulating inflammation by suppressing excessive IL-6 and TNF-α expression. It also promotes macrophage aggregation to release growth factors, aiding tissue repair and remodeling. Its potent antioxidant and anti-inflammatory properties regulate intracellular copper levels, enhance antioxidant capacity, and delay cellular aging. In pulmonary inflammation models, it mitigates lipopolysaccharide-induced acute lung injury and improves tissue inflammatory states. GHK-Cu benefits hair health by stimulating hair follicle cell activity, promoting melanin production, regulating energy metabolism, and aiding in hair loss improvement.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eConclusion\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eAs a blend of TB 500, BPC-157, KPV, and GHK-Cu, Klow's synergistic effects manifest through the overlapping and complementary regulation of multidimensional physiological functions. TB 500 promotes cell migration and angiogenesis, BPC-157 enhances tissue repair and inflammatory regulation, KPV focuses on immune balance and local anti-inflammation, while GHK-Cu functions in antioxidant defense, skin regeneration, and microenvironment optimization. Together, they form a closed-loop system of “repair-anti-inflammation-immune modulation-microenvironment enhancement.”\u003c\/p\u003e\n\u003cp\u003eUnder this synergy, TB 500 and BPC-157 accelerate cell proliferation and matrix synthesis, while KPV mitigates excessive inflammation by inhibiting the NF-κB pathway, creating a stable environment for repair. GHK-Cu's antioxidant properties reduce free radical damage to newly formed tissues, and its vasoprotective effects synergize with TB 500's angiogenesis function to enhance local blood supply. KPV's bidirectional immune modulation balances the immune activation triggered by BPC-157 and GHK-Cu, preventing immune dysregulation. This synergy not only shortens tissue repair cycles but also improves repair quality and reduces scar formation risk, offering comprehensive regulatory advantages in scenarios such as wound healing, chronic inflammation, and skin aging.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cp data-start=\"293\" data-end=\"654\"\u003e\u003cstrong\u003eFor Research Use Only\u003c\/strong\u003e\u003cbr data-start=\"321\" data-end=\"324\"\u003eThis compound is provided exclusively for in vitro laboratory research. It is not intended for human or animal consumption, diagnosis, treatment, or medical use. Not for dietary, cosmetic, or veterinary purposes. This product has not been evaluated by the U.S. Food and Drug Administration or any other regulatory authority.\u003c\/p\u003e\n\u003chr data-start=\"656\" data-end=\"659\"\u003e\n\u003cp data-start=\"661\" data-end=\"910\"\u003e\u003cstrong\u003eDisclaimer\u003c\/strong\u003e\u003cbr data-start=\"675\" data-end=\"678\"\u003eAll information is for educational purposes only. Humatide makes no claims regarding efficacy or safety. Purchasers are responsible for ensuring proper handling and use in compliance with all applicable laws and regulations.\u003c\/p\u003e\n\u003chr data-start=\"912\" data-end=\"915\"\u003e\n\u003cp data-start=\"917\" data-end=\"1259\"\u003e\u003cstrong\u003eTerms of Sale\u003c\/strong\u003e\u003cbr data-start=\"934\" data-end=\"937\"\u003eBy purchasing from Humatide, you confirm that you are a qualified researcher with the knowledge and facilities to safely handle and store research chemicals. All sales are final. Humatide assumes no liability for misuse, misrepresentation, or unintended consequences arising from the use of this product.\u003c\/p\u003e","brand":"Humatide","offers":[{"title":"80MG","offer_id":46003536560318,"sku":null,"price":90.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0748\/8667\/6670\/files\/KLOW.jpg?v=1781294115","url":"https:\/\/shop.humatide.com\/products\/bpc157-tb500","provider":"Humatide","version":"1.0","type":"link"}